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On the evidence question: The absence of Phase III human trial data for compounds like BPC-157 and TB-500 is a genuine clinical limitation, not a technicality

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Curcumin typically is not absorbed well in the body

Depending on the model, researchers may assess changes in molecular markers (e.g., gene expression or pathway readouts) to better understand how short peptides can influence age-related cellular processes

Well, for one it is known as the most powerful native antioxidant produced by the body