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When B12 is insufficient, these pathways slow down

Additionally, some individuals taking Mounjaro may have pre-existing conditions that independently increase their risk of B12 deficiency, such as previous bariatric surgery or concurrent metformin use (the MHRA has highlighted that metformin can reduce vitamin B12 levels)

The false-low b12 phenomenon complicates assessment further

Around 5-10% experience transient nausea, and 3-7% report occasional lightheadedness in the first week

Approximately 6% of people under age 60 and 20% of people over age 60 are vitamin B12 deficient

Unlike a typical FDA panel, several members make their living prescribing, researching, or selling peptide therapies, raising questions about how the debate will unfold