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The body then uses vitamin B12 for various functions, In a person with pernicious anemia, the immune system mistakenly attacks the cells that produce the intrinsic factor

are deficient in vitamin B12

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severe thiamine deficiency, while rare, can cause Wernickes encephalopathy in hyperemesis gravidarum, and inadequate B is associated with anemia and neurologic issues in the newborn

Macrophages can secrete various cytokines, such as TNF-, IL-1, IL-6, IL-7, IL-15, IL-18, IL-23

In contrast, metformin is commonly used during pregnancy for diabetes and polycystic ovary syndrome, and is compatible with breastfeeding