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Research involving MOTS-c focuses on its interaction with cellular signaling pathways associated with metabolic regulation, mitochondrial efficiency, and adaptive cellular responses under stress conditions

Findings are published in JAMA and presented simultaneously at the European Society of Cardiology Congress

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Furthermore, adding to the complexity of this process, allosteric activators have been described that bind to sites distinct from the orthosteric binding pocket of the receptor (Zhao et al., 2020), thereby necessitating a highly precise preselection of compounds to be used as lead candidates

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People with Type 2 diabetes have a higher risk of heart attacks and strokes GLP-1s may help reduce these risks