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PubMed Anisimov VN, Khavinson VKh, et al

For a broader picture of where CagriSema fits, see our GLP-1 trends in 2026 guide

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Current pharmacological therapies, including cholinesterase inhibitors (ChEIs) (e.g., donepezil, rivastigmine, galantamine) and N-methyl-D-aspartate (NMDA) receptor antagonists (e.g., memantine), offer only modest symptomatic relief without altering disease progression (Butterfield and Halliwell, 2019)

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