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The % difference in response between initial and time points is less than 10% for standard ( Table 7 )

This establishes a closed loop of barrier damageimmune activationneural sensitizationcentral feedbackinflammation amplification, which accounts for GERD chronicity and subtype heterogeneity, and elucidates the bidirectional relationship between emotional states and inflammation

Neuro Endocrinol Lett 2001;22:2514