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Deficiency can lead to malformed red blood cells (megaloblastic anemia) and impaired DNA synthesis in bone marrow cells

Theres also a practical consideration for RA patients: some biologic medications (methotrexate, for example) are associated with nausea and GI sensitivity

Effect of 5-caffeoylquinic acid on the NF-B signaling pathway, peroxisome proliferator-activated receptor gamma 2, and macrophage infiltration in high-fat diet-fed Sprague-Dawley rat adipose tissue

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