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Individuals who have had gastrointestinal surgery, such as weight loss surgery, may also have fewer cells through which to secrete stomach acid and intrinsic factor, inhibiting B12 absorption

No dose-escalation or maximum tolerated dose studies have been conducted, limiting understanding of safety at higher doses

It works by supporting tissue repair and recovery rather than directly increasing muscle mass or altering hormone levels

doi: 10.1136/gut.2010.216929 139 KobayashiYOhfujiSKondoKFukushimaWSasakiSKamataNet al

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