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2,21 Advanced atherosclerosis

Missing a dose by a day or two is manageable, but extended gaps allow the medication to clear the system and side effects to return when restarting

Intravenous administration is more likely to increase plasma carnitine concentration, yet homeostatic mechanisms tightly control blood concentration through metabolism and renal excretion: Up to 90% of 2 g of L-carnitine administered intravenously is excreted into the urine within 12 to 24 hours

Replacing the Estimated Allowed Amount With the Allowed Amounts Data Elements and the Count of Allowed Amounts Data Element a

Expert Opin Drug Metab Toxicol 15(11):913925

Winnenburg R, Bodenreider O (2013) Exploring pharmacoepidemiologic groupings of drugs from a clinical perspective