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Review of cardiovascular outcomes trials of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists

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Furthermore, long-term consequences and complications from elevated blood glucose levels include coronary artery disease, stroke, and diabetic retinal degeneration, which can cause blindness, kidney damage, and inadequate circulation in the lower extremities which may result in amputations [16]

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They modulate neuroinflammation, neuronal viability, A metabolism and synaptic functionkey determinants of AD progression