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Washout window: Most physicians recommend a 1 to 2 week gap between your last semaglutide injection and your first tirzepatide dose, based on semaglutide's 7-day half-life

That means that the act of growing a hair leads to melanogenesis, which causes excess free radical production, which increases the potential for DNA damage, and thus potentiates the loss of melanocyte stem cells, melanocytes, and thereby melanin

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Caloric deficit even a mild 300-500 calorie daily deficit dramatically improves outcomes

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