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In 2023, both were placed on a list of substances considered to be too high-risk for pharmacy compounding

Folate is not automatically appropriate Folic acid, folinic acid and methylfolate may improve selected conditions, including confirmed folate receptor antibody-related problems

doi: 10.1089/met.2020.0017

Separately, FDA lists GHK-Cu for injectable routes under safety concerns, citing immunogenicity risk and limited human safety data [8]

Because GHK-Cu does not target the same biological mechanisms as finasteride or minoxidil, it may be used topically as a complementary step

GHK-Cu works best as part of a consistent routine that also includes gentle cleansing, moisturizer and daily sunscreen