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In B cells, basal G6PD expression and activity are low, suppressed by transcription factors paired box protein 5 (PAX5) and Ikaros family zinc finger protein 1 (IKZF1)

Okonkwo UA, DiPietro LA

The pathophysiological features of type 2 diabetes and its metabolic complications (hyperglycemia, hyperinsulinemia, and insulin resistance) play a crucial role in the development and progression of both heart failure and cognitive dysfunction

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[PMC free article: PMC2439522] [PubMed: 18500381] 44