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Dry mouth patients need to use a high-fluoride content toothpaste to compensate for the lack of salivary fluoride

These include: Nausea (reported in a significant proportion of participants, particularly during dose escalation) Vomiting and diarrhoea Constipation and abdominal discomfort Decreased appetite , which, whilst contributing to weight loss, can occasionally lead to inadequate nutritional intake Most gastrointestinal effects were described as mild to moderate in severity and tended to diminish over time

Furthermore, GLP-1 RAs exhibit vasodilatory effects by promoting endothelial nitric oxide (NO) synthesis, enhancing endothelial function with a consequent reduction of vascular resistance and an improvement in cardiac afterload [45, 46]

These hormones play a vital role in keeping your metabolism healthy and balanced