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A nationwide cohort study from Sweden and Denmark found no significant increase in suicide deaths among GLP-1 RA users compared to Sodium-glucose cotransporter-2 (SGLT2) inhibitors, and even reported a lower incidence of combined suicide and self-harm outcomes (HR 0.83) [47]

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The pen needle is also very short, typically 4 to 5 mm, meaning it barely penetrates the subcutaneous layer