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IGF-IR determines the fates of BCR/ABL leukemia

2.2.1.3 Mechanism of SLC7A11 and p53 in the regulation of ferroptosis Suppression of SLC7A11, a key component of system Xc , induces intracellular GSH depletion, subsequently initiating ferroptosis (Guo et al., 2022

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With APAP overdose, however, so much NAPQI is formed that glutathione stores become depleted resulting in NAPQI-induced cytotoxicity

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And with in vitro human primary mast cells services, we can go even deeper to identify the adverse effects mediated by these key immune cells