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This will require strong evidence from trials that such interventions in asymptomatic or early-stage individuals truly alter the trajectory studies like the Brain-Microbiome project in prodromal AD and the TopHat trial in REM-sleep-behavior-disorder (prodromal PD) are beginning to explore this

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Similar content being viewed by others Introduction Reactive oxygen species (ROS) are expected products of oxidative metabolism, and must be tightly regulated in the normal brain