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The engineered TCR used for this experiments, 1G4, is an enhanced affinity TCR previously reported 53

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It is important to follow recommended dosing guidelines and consult a healthcare practitioner if you are pregnant, nursing, or taking medications

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Gastrointestinal distension by ISF significantly reduced short-term food intake without aversive behavior, and this effect was significantly attenuated by pretreatment with GLP-1R antagonist or chemical ablation of vagal sensory neurons (Fig