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It remains in Phase 3 clinical trials

Dedicated, prospective studies with adequate sample sizes, long-term follow-up, and comprehensive metabolic phenotyping are urgently required to validate these preliminary observations and establish evidence-based, genotype-specific treatment approaches

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Some patients lower their tirzepatide dose and also cut calories further, attempting to "pre-empt" any regain

Yet between meals, sometimes for months, insulin requirements are minimal

1 Study Design