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In research settings this pathway triad is studied for effects on appetite signals, gastric emptying, insulin dynamics, and energy expenditure

What happens to the heart when people stop GLP-1 drugs

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Friedrichsen BN, Neubauer N, Lee YC et al

By modulating the translocation of the RXR binding partner (orphan nuclear receptor Nur77), from the nucleus to the mitochondria it inhibits cell growth and induces apoptosis (Lee et al., 2005)

Physiologic and pathophysiologic roles of extra renal CYP27b1: case report and review