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The primary symptoms of gastroparesis include: Nausea and vomiting , often of undigested food consumed hours earlier Early satiety (feeling full after eating only small amounts) Abdominal bloating and distension Upper abdominal pain or discomfort Heartburn or gastro-oesophageal reflux Poor appetite and unintentional weight loss Blood glucose fluctuations in people with diabetes Gastroparesis has several recognised causes

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Key Takeaways GLP-1RAs operate via different neurobiological pathways by modulating reward, stress and metabolic signals rather than just blocking alcohol reward signals or managing withdrawal

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