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Further Reading For wider scientific background on peptide and incretin research, researchers can review public information from PubMed and ClinicalTrials.gov

Genome-wide association study To account for potential population stratification amongst our study participants within ancestry categories, we projected everyones genotype by principal components using cohort-wide standardized genotypes

The open-label trial included 1,428 participants and was conducted between October 2020 and November 2022

[DOI] [PMC free article] [PubMed] [Google Scholar] 229.Poltorack CD, Dixon SJ

Dual GIP & GLP-1 Agonists While Single GLP-1 RAs focus on one incretin pathway (the GLP-1 pathway), Dual GIP and GLP-1 agonists double down by also acting on another pathway involved in glucose regulation and energy balance

Cognitive function was tested using the National Institute of Health Toolbox Cognitive Battery at baseline and 12 weeks