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Vitamin B12 Shots vs B12 Supplements When it comes to boosting your Vitamin B12 levels, both supplements and shots can be effective, but there are some differences to consider

However, the evidence base is still developing

That is intentional: the two vial sizes reflect two different documented protocols and two different concentration setups, and it is a reminder never to eyeball a dose across vial sizes

Sarah Watley, medical director with stacked peptides

Mechanism of Action: Cyanocobalamin is a synthetic form of Vitamin B12. As a crucial cofactor in DNA synthesis, red blood cell production, and neurological function, this form of Vitamin B12 facilitates critical biochemical pathways

If we know the amount of B12 absorbed from various supplemental doses of cyanocobalamin, we can create recommendations to meet the predicted amount of B12 absorbed per week by the IOM and EFSA recommendations