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Chronic hyperglycemia in diabetes increases the production of AGEs, leading to diabetes related complications

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In this state, mutations of the APP gene augment the assembly of aberrant insoluble A, leading to the formation of amyloid plaque (Tomiyama and Shimada 2020)

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Drinking alcohol can trigger a sore throat due to its dehydrating effects and tendency to cause inflammation, leading to dryness and irritation of the throat tissues

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