Subcellular incubations Each of the 23 aromatic amide test compounds (bicalutamide, niclosamide, flutamide, lidocaine, prilocaine, propanil, acetanilide, 2-acetamidophenol, 3-acetamidophenol, acetaminophen, 3-nitroacetanilide, 4-nitroacetanilide, 3-fluoroacetanilide, 4-fluoroacetanilide, 2-methylacetanilide, 3-methylacetanilide, 4-methylacetanilide, N -methylacetanilide, benzanilide, salicylanilide, 4-bromo-2-methoxy- N -phenylbenzamide, N -phenylurea, 2-chloro- N -phenylacetamide) were dissolved in DMSO at a concentration of 10 mM and stored at 20 C until required (maximum storage time three months)
The other cannot
But children can develop it too, especially boys before puberty
there is no ongoing regulated program to update the safety picture
Science 317 , 1355 (2007)
Euglycemic diabetic ketoacidosis associated with SGLT2 inhibitors: a systematic review and quantitative analysis