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The resulting NPs displayed tenfold greater antioxidant activity than conventional NPs and demonstrated therapeutic efficacy against cancer in both in vitro and in vivo models (145)

J.ZanoveliJ

This unfavorable physicochemical profile also culminates in non-specific tissue distribution, where high LogP promotes avid binding to biological membranes and plasma proteins

318,319 NOXs in immune cells, such as macrophages and neutrophils, are primarily responsible for ROS production and termed respiratory bursts during phagocytic bacterial killing

The highest levels of GSH are found in our heart, muscle tissues and the liver

A., McPhee, A