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External factors like toxins, diet, and medication can alter gut microbiota composition (Izco et al., 2021)

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If your organs are working overtime to process alcohol, a substance like creatine will not be as efficiently digested and absorbed. Dehydration Proper hydration makes a big difference when it comes to the absorption of creatine, Bogden says

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Easy on the Stomach: Cheap powders often sit in your gut undigested, drawing water and causing cramps