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If a prescriber determines the benefit justifies the risk in a specific case, the lowest available dose (0.5 mg) should be used no more than twice weekly, with biweekly copper monitoring and a predefined stopping rule

The Cleveland Clinic plans to further study how the gene works over the next two years, he said.

Losing weight can lead to some loss of muscle as well as fat

Limited Human Data: Very few human clinical trials exist, and those that do are generally small-scale, preliminary investigations

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