Another drug in development, retratrutide, works on three receptors: GLP-1, GIP, and the glucagon receptor
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Zhang Y, Nguyen TTT, Shang E, Mela A, Humala N, Mahajan A, et al
I would recommend them to anyone and everyone I know
In trials by Xie and colleagues, 47% to 84% of participants reported GI disturbances, similar to real-world use observations
More studies are needed before ALA can be recommended to treat these conditions