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doi: 10.1016/j.bioorg.2025.109370 35 HuszarDLynchCAFairchild-HuntressVDunmoreJHFangQBerkemeierLRet al

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"While I know words can never be enough, I believe an apology is necessary to recognize the harm and irreversible loss your community has suffered." According to the National Enquirer , there have been multiple lawsuits accusing AI chatbots like ChatGPT of worsening users' delusions and mental health crises, including one case involving 23-year-old Zane Shamblin , whose family alleged an AI chatbot encouraged him before his July 2025 suicide

Selective GHSR activation

However, it causes mast cells to release more histamine while inhibiting the DAO enzyme, which breaks down histamine, especially in your gut and uterus

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