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It mimics the GLP-1 hormone that our body naturally produces in the gut after eating

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An obvious decrease of up to 59% of relative total trabecular density was recorded compared to normal control samples with a significant decrease of the trabecular thickness, and a significant loss of osteoblastic activity was shown with focal records of trabecular cracks and fissures with a marked increase of intertrabecular marrow spaces accompanied by remarkable hypoplasia of bone marrow with significant vacuolization recorded

doi: 10.1080/14656566.2024.2366993 47 ZhaoXWangMWenZLuZCuiLFuCet al

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The immunosuppressive burden here is driven entirely by prednisone