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Zinc transporter ZIP7 is a novel determinant of ferroptosis

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This is an inherited genetic disease called pyroglutamic aciduria which manifests as hemolytic anemia and metabolic acidosis, causing neurological disorders and vulnerability to bacterial infections, and which can be classified as mild, moderate or severe depending on the severity of the symptoms

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On DIV12 the neurons were fixed (4% paraformaldehyde, 3% sucrose, 60 raM PIPES, 25 mM HEPES, 5 mM EGTA, 1 niM MgCl 2 , pH 7.4) for 20 min at room temperature and mounted