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What the GLP-1 class data tells us A systematic review published in PMC (2025), analyzing 5 studies encompassing 2,905 adult patients, found significant associations between GLP-1 receptor agonist use and hair loss

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GLP-1 receptor agonists work through several mechanisms: they enhance insulin secretion when blood glucose levels are elevated, suppress glucagon release (which reduces glucose production by the liver), slow gastric emptying, and promote satiety through effects on appetite centres in the brain

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It remains an investigational compound in Phase 3 clinical development

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