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Both of these barriers often get damaged in autoimmune diseases

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That works at first, but the hidden cost is fragmentation: when reactions recur or change during dose escalation, patterns get missed, delays in clinician decisions occur, and anxiety spikes because nobody can show a clean, time-stamped record

Summary: The correct dosage of B12 for healthy UK adults is 1.5 micrograms daily for maintenance, whilst treatment of deficiency requires substantially higher doses of 1,0002,000 g orally or 1 mg intramuscular injections

doi: 10.1111/dom.14110 [DOI] [PMC free article] [PubMed] [Google Scholar] 152