(3) Inhibiting Adipose Tissue Inflammation and Improving the Adipose Microenvironment In obesity, adipose tissue develops chronic lowgrade inflammation with abundant release of proinflammatory factors (such as TNF and IL6), disrupting the adipose microenvironment, further worsening fat metabolic abnormalities and insulin resistance, and forming a vicious cycle
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Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression
Eosinophils from patients with severe asthma were reported to be more activated than those with non-severe asthma, and these eosinophils produce higher levels of ROS and EETs
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