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In yeast, a specific roGFP biosensor targeting mitochondria can be used to compare ROS production in normoxic and hypoxic conditions (AN310: Mitochondrial oxidant generation follows oxygen deprivation and re-oxygenation)

Instead, research suggests it works by inhibiting Hepatocyte Growth Factor Activator Inhibitor (HAI-1), an enzyme that normally limits HGF activity

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p 20 mL/min per 1.73 m 2 , should be treated with SGLT2