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& Dolores Dor Eccles Professor of Ophthalmology & Neuroscience, Wilmer Eye Institute, The Johns Hopkins School of Medicine involving oxidative stress in the retina provided impetus for exploring small molecule antioxidant therapies

Most importantly, we observed that the levels of GPX4 and ferrous iron of CRC DTP cells were significantly increased, and consequently caused selective sensitivity to GPX4 inhibitor-induced ferroptosis

We also tested the effect of chronic feeding by incorporating MCT and triheptanoin into pelleted mouse diets at 35% of total calories

doi:10.1016/j.cell.2012.04.026 Brady CA, Jiang D, Mello SS et al (2011) Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression

The results are presented in Table 2

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