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FDA green-lights tirzepatide, marketed as Zepbound, for chronic weight management

Self-prescribing unlicensed peptides carries real and potentially serious health risks

In large obesity trials using full doses, once-weekly semaglutide and tirzepatide led to substantial average weight loss and improved metabolic markers in adults with obesity.[13] For example, the STEP 1 trial of once-weekly semaglutide in adults with overweight or obesity and the SURMOUNT-1 tirzepatide obesity trial both showed strong weight-loss effects when combined with lifestyle changes

GLP-1 Medical Weight Loss Program in New Jersey GLP-1 medications are most effective with sustained support

The Phase 2 trial published in the New England Journal of Medicine in 2023 confirmed this pharmacokinetic profile