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N.WangH.HeL.RongX.et al (2023)

Konovalova The Russian State Center for Animal Feed and Drug Standardization and Quality Email: [email protected] ORCID iD: 0000-0001-5306-7303 Head of the Preclinical Research Department 5 Zvenigorodskoe highway, Moscow, 123022, Russian Federation Valentina V

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This allows for targeted modulation of deep brain regions or specific neural circuits that are difficult to reach with conventional techniques

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However, when the structural and functional integrity of neural cells is compromised and the permeability of the bloodbrain barrier increases, it disrupts blood biomarkers, allowing GFAP to be released from tissues into the bloodstream