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Although adipose tissue allows storage of excess calories in periods of overnutrition, in obesity, adipose tissue metabolism becomes dysregulated and can promote metabolic diseases

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Potential risks include infection, scarring, changes in nipple sensation, difficulty breastfeeding, asymmetry, and in rare cases, partial or total loss of the nipple or areola

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In the withdrawal cohort, regaining half of the lost weight raised insulin resistance by roughly 35% to 40%, and blood pressure rose as weight returned. Taper frameworks combine about 0.7 g of protein per pound with resistance training before the drug signal fades