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Randomization and blinding The patients were assessed for eligibility and were randomly assigned to groups based on whether they were treated by PEID (single surgery

These symptoms are usually short-lived and should subside within a few hours

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FDAs staff reviewers said before the meeting they couldnt find strong evidence to support any of those uses

Therefore, some studies have attempted to embed icariin-containing nanogels in poloxamer to develop an icariin nanogel self-assembled thermosensitive hydrogel system, which adheres to the nasal mucosa and prolongs drug release time, thereby improving its bioavailability

Early synaptic dysfunction or synaptopathy at the level of inhibitory interneurons within the entorhinal cortex and CA3 hippocampal subregion leads to hyperactivity of pyramidal cells, which appears to play a role in the progression of AD neuropathology (e.g., tauopathy) (271, 272)