10.1016/j.cell.2018.09.048 56 LincoffA
Brown MJ, Willis T, Omalu B, Leiker R
The goal is to lose fat, preserve muscle, and improve long-term movement, living, and functioning
Further research is needed to fully understand the mechanisms of action and potential uses of these metabolites
These cytokines activate JAKs, which in turn phosphorylate STAT proteins, leading to their dimerization and nuclear translocation, where they initiate the transcription of pro-inflammatory genes (51)
This often includes athletes with sports-related injuries like muscle tears or tendonitis, people recovering from surgery, or those with soft tissue damage