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It adhered to the guidelines specified in the Cochrane Handbook for Systematic Reviews of Interventions and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) (Appendix 1) [17,18]
DOI: 10.1038/s41467-025-60844-9
The decline was also not evenly spread, as the largest drops were seen in men and people living with joint or muscle pain
These ones, not so, although they are in-store only and not available on-line
As these treatments move beyond specialist use into the mainstream, they are influencing expectations around portion size, satiety, nutrient density and added functionality