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Methionine supplementation at very high doses may increase homocysteine levels if B12 and folate are insufficient
Clinical laboratories must shift from static interpretation to a therapy-aware, dynamic framework, integrating drug exposure into reporting systems, updating reference intervals, and adopting AI-driven tools to avoid large-scale diagnostic errors in the GLP-1RA era
Conclusion We found evidence for the role of lower GSH in patients with MDD in the occipital region of the brain, a difference which is not found in other brain regions or in combined brain region studies
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