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Prime your pen: Press the needle button and dial up 2 units to let insulin out into the air

Mithieux G, Misery P, Magnan C, Pillot B, Gautier-Stein A, Bernard C, et al

Joint pain during GLP-1 treatment may result from rapid weight loss altering biomechanical loading on joints, increased physical activity levels, or pre-existing musculoskeletal conditions such as osteoarthritis, which are common in people with type 2 diabetes or obesity

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Weeks 5-8 (5mg): This is when things start to shift

Previous studies have shown that internalization of these receptors following ligand stimulation is more pronounced in IR than IGF1R (14), and this effect is decreased in insulin-resistant obese subjects and obese type 2 diabetic patients (24)