The carrier base matters substantially for topical GHK-Cu dosing protocols
Copper compounds are also used as actives or excipients in cosmetic and pharmaceutical products, e.g., copper peptide for skin regeneration purposes, cupric aspirinate and cupric salicylate for rheumatoid arthritis treatment, copper conjugated dendrimer for anti-tumoral activity, and copper liposome for enhanced stability of doxorubicin 5,6,7,8,9
For example, control experiments with millimolar GSH and a monothiol glutaredoxin mutant to exclude a monothiol mechanism often appear to be missing 40,41,87
Not everyone is an ideal candidate
WangQYanTJiangWHuNZhangSYangPet al
This overstimulation leads to a massive and irreversible differentiation of the entire reserve of stem cells into active melanocytes