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11 Glutathione is a fragile nutrientbecause it breaks down so easily in the GI tract, glutathione is not readily absorbed and only small quantities reach the bloodstream

& Lavergne, J

Additionally, PD patients present deficiencies in mitochondrial complex I in the SN, suggesting that a defect in this complex could contribute to neuronal degeneration in PD [25]

Interactions of melphalan with glutathione and the role of glutathione S-transferase

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Conclusion Glutathione offers potential health benefits like detoxification and antioxidant support, but its effectiveness can be reduced by factors like alcohol and certain medications