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KBP-089 is currently being tested in a phase I clinical trial in patients with type 2 diabetes (159)

Genotyping of key genes regulating platinum metabolism and accumulation (e.g., GSTP1) and DNA damage repair (e.g., ERCC1, BRCA1/2) should be performed to screen patients at high risk of excessive accumulation and severe toxicity, as well as those most likely to benefit from platinum-based regimens

Good Lab Practices: Use appropriate PPE, follow institutional protocols, and reference your labs chemical hygiene plan

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