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And it provides the medium where bacteria can grow, introducing biological contamination on top of chemical degradation

Glutathione (GSH) is a central component of the antioxidant defense system, and disruption of GSH homeostasis can lead to the accumulation of pyroglutamate (PGA), which is detectable in plasma

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COCs containing anti-androgenic progestins share spironolactone's mechanism limitation: once stopped, hormonal acne frequently returns