Programmable scheduled release microneedle patches (dissolvable) containing the GLP-1 drug semaglutide are under trial
"The microdosing strategy has some attractive benefits, including helping to mitigate side effects and being able to customize the dose to the minimum efficacious dose for individual patients," says Katie Sorensen , a nurse practitioner specializing in GLP-1 medications who was not involved in Burgess' treatment
PMID: 38741261.
In one study (again, with a standardized breakfast), at the five-month mark (i.e
In one phase 2 study: Pancreatitis was reported in about 0.4% of participants (1 out of 267) Gallbladder issues affected roughly 1.1%, with no cases in the placebo group Heart rhythm changes were reported more often in people taking retatrutide (about 6% compared to 3% with placebo) Liver enzyme increases were rare (around 1%), and overall liver health markers stayed stable over time
On the flip, the days you indulge in heavier, greasier foods (which is OK sometimes) may make you feel less motivated and more sluggish
